This document contains guidance for Integrated Modular Avionics (IMA) developers, application developers, integrators, certification applicants, and those involved in the approval and continued airworthiness of IMA systems in civil certification projects. The guidance describes the objectives, processes, and activities for those involved in the development and integration of IMA modules, applications, and systems to incrementally accumulate design assurance toward the installation and approval of an IMA system on an approved aviation product as differentiated from traditional federated aviation system architectures. This document is applicable to all parties involved in the development, integration, verification, and validation of IMA systems. The guidance in this document is focused on IMA-specific aspects of design assurance.